Monday, April 27, 2015

Where do our expressions come from? And the Gates of Benyamin



 Learn From Positive Role Models 

Learn from positive role models. Every person you meet today will have positive qualities, habits, and strengths that you can learn from. Learn from role models who handle difficult situations calmly and effectively.

Love Yehuda Lave




 


  Just in case you always wondered where the expression came from…

 A SHOT OF WHISKY
 In the old west a .45 cartridge for a six-gun cost 12 cents, so did a shot glass of whisky.  If a cowhand
 was low on cash he would often give the bartender a cartridge in exchange for a drink.  This became known
 as a "shot" of whisky.
 

THE WHOLE NINE YARDS
 American fighter planes in WW2 had machine guns that were fed by a belt of cartridges. The average plane
 held belts that were 27 feet (9 yards) long.  If the pilot used up all his ammo he was said to have given it the
 whole nine yards.
 
 
BUYING THE FARM
 This is synonymous with dying.  During WW1 soldiers were given life insurance policies worth $5,000.  This
 was about the price of an average farm so if you died you "bought the farm" for your survivors.
  
 
IRON CLAD CONTRACT
 This came about from the ironclad ships of the Civil War.  It meant something so strong it could not be
 broken.
  
 
PASSING THE BUCK/THE BUCK STOPS HERE
 Most men in the early west carried a jack knife made by the Buck knife company.  When playing poker it was
 common to place one of these Buck Knives in front of the dealer so that everyone knew who he was.  When it was
 time for a new dealer the deck of cards and the knife were given to the new dealer.  If this person didn't
 want to deal he would "pass the buck" to the next player.  If that player accepted then "the buck stopped there".
 
 
RIFF RAFF
 The Mississippi River was the main way of traveling from north to south.  Riverboats carried passengers and
 freight but they were expensive so most people used rafts.  Everything had the right of way over rafts
 which were considered cheap.  The steering oar on the rafts was called a "riff" and this transposed into
 riff-raff, meaning low class.
 
 
COBWEB
 The Old English word for "spider" was "cob".
 
 
SHIP STATEROOMS
 Traveling by steamboat was considered the height of comfort. Passenger cabins on the boats were not numbered. 
 Instead they were named after states. To this day cabins on ships are called staterooms.
 
 
SLEEP TIGHT
 Early beds were made with a wooden frame.  Ropes were tied across the frame in a crisscross pattern.  A straw
 mattress was then put on top of the ropes.  Over time the ropes stretched, causing the bed to sag.  The owner would then have to tighten the ropes to get a better night's sleep.
  

SHOWBOAT
These were floating theaters built on a barge that was pushed by a steamboat.  These played small towns along
the Mississippi River. Unlike the boat shown in the movie "Showboat" these did not have an engine.  They were 
gaudy and attention grabbing which is why we say someone who is being the life of the party is "showboating".
 

OVER A BARREL
In the days before CPR a drowning victim would be placed face down over a barrel and the barrel would be
rolled back and forth in an effort to empty the lungs of water.  It was rarely effective. If you are over a barrel you 
are in deep trouble.
 

BARGE IN
Heavy freight was moved along the Mississippi in large barges pushed by steamboats.  These were hard to control
and would sometimes swing into piers or other boats. People would say they "barged in".
  

HOGWASH
Steamboats carried both people and animals. Since pigs smelled so bad they would be washed before being
put on board. The mud and other filth that was washed off was considered useless "hog wash".

 
CURFEW
The word "curfew" comes from the French phrase "couvre-feu", which means "cover the fire". It was used to
describe the time of blowing out all lamps and candles. It was later adopted into Middle English as  "curfeu", which 
later became the modern "curfew". In the early American colonies homes had no real fireplaces so a fire was built in the
center of the room.  In order to make sure a fire did not get out of control during the night it was required that, by an agreed upon
time, all fires would be covered with a clay pot called-a "curfew".
 

BARRELS OF OIL
When the first oil wells were drilled they had made no provision for storing the liquid so they used water barrels.  That is why, to this day, we speak of barrels of oil rather than gallons.
 

HOT OFF THE PRESS
As the paper goes through the rotary printing press friction causes it to heat up. Therefore, if you grab the paper right off 
the press it was hot. The expression means to get immediate information.


On Yom Hatzamut we go to visit with the gang in Piz Gat Zev
Binyamin Canyon and Mukhamas



https://youtu.be/1AJAsdkeNHM





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Sunday, April 26, 2015

21 Photos Of Nature Winning The Battle Against Civilization | And Above and Beyond sample



Update Your Understanding

The Sages (Talmud, Yoma 29a) tell us that it is more difficult to understand an idea we already know than one that is new to us. This is because we feel we already understand it and do not concentrate on it as much as we should. Also, we tend to rely on the level of understanding we had when we were younger and less mature.

Today, think about a concept that would enhance your life greatly if internalized and integrated. Reflect on that idea with your present knowledge and life experience.

Love Yehuda Lave

This is a follow up to last week's post about the young Jewish lady who saved a whole plane.
Fiction predicts truth (and sometimes the other way around), when a young Jewish William Shatner appeared on the Twilight Zone many years ago:


Here's a summary of a similar incident involving Captain Kirk before he became Starfleet Commander:

Watch "Shatner v The Gremlin -- Two Minute Twilight Zone Project --  Nightmare at 20,000 feet" on YouTube

https://youtu.be/dar2HKImK-0

Now to a different movie subject.
This movie with the short below will play here in Israel On Tuesday at the Beth Am Center

 

This short video holds the key to Israel's survival as a nation back in May 1948. The Arab nations were within 10 miles of Tel Aviv, with a 10,000 man force, ready to totally destroy the new country of Israel.  All that stood in the way were four Messerschmitt BF-109's left behind by the Nazis in the Czech Republic, hurriedly assembled in hangars and never test flown, and piloted by volunteer American (Jewish) pilots. I can't wait to see the documentary.

 

THIS IS A TRUE STORY, NOT KNOWN BY MANY . The only FOUR (4) Airplanes Israel had when the War of Independence (May 1948) began were smuggled in from Czech Republic. They were German Messerschmitt BF-109's.  They were assembled overnight in Tel Aviv and were never flight tested.This is a short video about their pilots. Watch it. You will not be disappointed.    http://vimeo.com/54400569


Watch these amazing Pictures of Nature taking back abandoned properties



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Friday, April 24, 2015

Israel Update - Jerusalem: Facts and Figures and PM Benyamin Netanyahu lays a wreath at Mount Herzl


Cultivate Gratitude

Lack of gratitude is at the root of discontent. In order to be consistently serene, we must master the attribute of being grateful to the Creator for all His gifts. As the Torah (Deuteronomy 26:11) states, "Rejoice with all the good the Almighty has given you." This does not negate our wanting more. But it does mean that we have a constant feeling of gratitude since as long as we are alive, we always have a list of things for which to be grateful.


Love Yehuda Lave



 






Jerusalem: Facts and Figures
by Yvette Alt Miller




Jerusalem: Facts and Figures





Author Biography:

Yvette Alt Miller earned her B.A. at Harvard University. She completed a Postgraduate Diploma in Jewish Studies at Oxford University, and has a Ph.D. In International Relations from the London School of Economics. She lives with her family in Chicago, and has lectured internationally on Jewish topics. Her book Angels at the table: a Practical Guide to Celebrating Shabbat takes readers through the rituals of Shabbat and more, explaining the full beautiful spectrum of Jewish traditions with warmth and humor. It has been praised as "life-changing", a modern classic, and used in classes and discussion groups around the world.







Netanyahu: Israel 'Adds Life' on Remembrance Day

Israel "adds life" while hate-filled terrorists try to "take life," PM Netanyahu said on Remembrance Day at Mt. Herzl.
Published: April 22nd, 2015


PM Binyamin Netanyahu lays a wreath at Mount Herzl to honor victims of terror on Israel's Remembrance Day.

PM Binyamin Netanyahu lays a wreath at Mount Herzl to honor victims of terror on Israel's Remembrance Day.
Photo Credit: Gili Yochanan / POOL

Prime Minister Binyamin Netanyahu focused special attention in honoring the victims of terror Wednesday at Remembrance Day ceremonies at Jerusalem's Mount Herzl military cemetery.

Joining the prime minister for the ceremony were President Reuven Rivlin and IDF Chief of General Staff Lt.-Gen. Gadi Eisenkot. Both lay wreaths for the victims of terror.

The designation is a relatively new addition to ceremonies that once were held to commemorate only the fallen among Israel's soldiers. It was recognized, however, that those who die simply because they are citizens of the state are as worthy of being a "soldier of Israel" as any uniformed defender.

Bereaved Israelis flocked to the graves of fallen soldiers at the cemetery, paying their respects to troops killed in wars since 1860 as well as victims of terror.

Since the close of Israel's War of Independence in 1948, 2,538 have died in terrorist attacks – including 31 in the past year alone.

The hatred of terrorists "is blind; for them we are all targets," the prime minister said in addressing participants. "While they try to take life, we add life." He listed the attacks in the past year in which precious Jewish lives have been stolen and blood shed in the State of Israel by murderous terrorists.

There is no difference between IDF soldiers on the homefront or those in the field, civilians involved in their daily affairs or those serving their time in army reserves, he said.

All are targets.

But the prime minister also warned that the radical Islamist terror once believed to be exclusive to the Middle East has made its way abroad and now has spread to Europe.

Attacks against Jews in countries like France – where the week-long reign of terror in Paris horrified millions this past January and left more than a dozen people dead – are becoming more common. Four people died at the Hyper Cacher kosher grocery store during that massacre.

Such activity, said Netanyahu, perversely seems to draw the admiration of many of Israel's neighbors, rather than disgust.

"They admire murderers," the prime minister noted. "The more they murder, the more they admire them."

For Israel to achieve peace with her neighbors, he said, they must "stop the incitement and the admiring of murderers. That's not how you make peace."

About the Author: Hana Levi Julian is a Middle East news analyst with a degree in Mass Communication and Journalism from Southern Connecticut State University. A past columnist with The Jewish Press and senior editor at Arutz 7, Ms. Julian has written for Babble.com, Chabad.org and other media outlets, in addition to her years working in broadcast journalism.










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Thursday, April 23, 2015

WATCH: So many reasons to love Israel on Israel Independence day and a woman saves lives by showing her indepence


Learn To Differentiate

If your mind is focused on an insignificant incident, it can destroy your happiness if you allow it to. To feel happy, your mind has to be free of pains and misfortunes.

Learn to differentiate between productive thinking about problems as a means of solving them, and counterproductive dwelling on misfortunes which gains nothing positive and destroys your quality of life.


Love Yehuda Lave



Dear Friends

At the beginning of the 67th year of Israel's independence I am pleased to send you a short summary of the currents in contemporary Israeli society in the State of Israel, where today 6,333,800 million Jews are living 1255 cities villages, mosha​


​vim and kibbutzim throughout the Land of Israel.

Together with Am Yisrael and all Jews wherever they are living, we wish for the fulfillment of our prayer:

אוֹר חָדָשׁ עַל צִיּוֹן תָּאִיר וְנִזְכֶּה כֻלָּנוּ מְהֵרָה לְאוֹרוֹ""

"May a new light shine on Zion and may we all merit its light"

 

With best wishes

חֲבֵרִים כָּל יִשְׂרָאֵל 

Chaverim Kol Yisrael - All Israel are friends
.

In honor of Yom Ha'atzmaut, we wanted to capture and share what Olim love about living in Israel. As we crisscrossed Israel, we discovered Olim who are building the country, giving back, thriving and enjoying their favorite pastimes. Click on the video below to see their stories.
 
Thousands of Olim merit to make Aliyah and live the dream. This is what they love about their lives in Israel.

Chag Atzmaut Sameach!


The Young Woman who Saved an Airplane

Everyone told her to sit down, but Mussie Weinfeld insisted something was wrong with the plane.

How far would you go to stand up for what you thought was right? Could you withstand yelling, threats and hostility? Would you be able to shrug off mockery and ridicule – or even disobey direct orders – and keep insisting that you were right?

That was the challenge facing Mussie Weinfeld on a recent flight from Tel Aviv to New York, as she prepared to return home after spending a special Passover in Israel. As the 22-year old teacher from Crown Heights, Brooklyn, settled in her window seat on a TransAero flight scheduled to leave Israel's Ben Gurion airport late Saturday night, April 11, 2015, and fly to New York via Moscow, she thought something seemed amiss.

"There was a very loud and strange noise on my side of the plane. I probably was extra scared because of what's going on recently with (crashes of) airplanes and I felt really uncomfortable with it," Mussie recalls. She also thought something didn't look right with the plane's wing. Concerned, Mussie shared her observations with passengers sitting near her, but they "laughed it off and said it was just noises from the engines," Mussie's father, Rabbi Kalman Weinfeld, recalled after speaking with his daughter.

At that point, the plane started taxiing towards the runway. "When the plane actually started moving I got even more scared," Mussie recalls, "and I said I have to do something." She unbuckled her seatbelt and stood up. As her father reported, "The flight attendants, who themselves were already seated and buckled in, instructed her to return to her seat. When she told them her concerns about the plane they too laughed at her. She insisted that she will not fly on the plane if they didn't check it out."

The flight attendants threatened the young woman, yelling at her to return to her seat, but Mussie refused. "I said, 'I don't want to sit down – I want you to go do something about it.' Then when I got back to my seat everyone took off their seat belts. Nobody wanted to take off now."

The airplane returned to the gate, for – airline officials announced – a 45-minute safety check. Nearly two hours later, however, it became clear the plane was unsafe to fly, and passengers were asked to return to the airport the following day to fly home on a different aircraft. Turns out Mussie was right; there was indeed a problem with the aircraft's wing. The synchronism slats on the wings' edges which allow for proper movement of airplane wings were broken. TransAero later insisted that they were in fact in the process of detecting the problem right before takeoff.

Realizing that the young teacher in their midst had saved them all from a potential tragedy, many of the travelers, who just hours before had mocked and yelled at Mussie, came over "and profusely thanked her for saving their lives," her father explained.

Mussie herself was modest about her role. "Everyone was thankful at least that we didn't take off with that plane," she said simply.

How many of us would have been able to stand up to such enormous social pressure and ridicule? By insisting that her concerns be checked out, Mussie Weinfeld embodied Hillel's maxim: "In a place where there are no leaders, strive to be a leader" (Ethics of the Fathers, 2:6). We all have the responsibility to take a stand and do what's right, to go against the grain and make our voices heard, even in the face of mockery and ridicule.

Whether or not TransAero was aware of the damage, as they claim, there is no question that Mussie Weinfeld demonstrated remarkable tenacity in refusing to go back to her seat, disobeying the flight attendants' orders and not trusting those who should seemingly know better than her.






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Wednesday, April 22, 2015

An Obituary printed in the London Times ...


Try As Much As Possible

Rabbi Yisroel Salanter used to say, "There is no greater illness than discouragement."

At times a person may take note of all his faults and failures and give up hope of improving. But when it comes to monetary wealth, a person tries to gather as much money as possible even if he will not become wealthy.

Someone suffering physical pain also tries to alleviate some of the pain even if he is unable to bring about a complete cure. Rabbi Salanter said our attitude towards refraining from evil and performing good deeds should be the same. Even if someone will be far from perfect, he should at least try to do as many good deeds as possible and refrain from violating as many prohibitions as he can.


Love Yehuda Lave




An Salute to our soldiers on the remembrance day for our dead heroes in Israel

https://mail.google.com/mail/u/0/?tab=cm#inbox/14cd5a613a716895?projector=1




The Amazing Fly Geyser in Nevada

https://www.youtube.com/watch?v=_GXF_iVPRBU












Six Jewish Strategies for Spiritual Growth

 
 
 
 

An Obituary printed in the London Times.....Absolutely Dead Brilliant!!

Today we mourn the passing of a beloved old friend, Common Sense, who has
been with us for many years. No one knows for sure how old he was, since his
birth records were long ago lost in bureaucratic red tape. He will be
remembered as having cultivated such valuable lessons as:

- Knowing when to come in out of the rain;
- Why the early bird gets the worm;
- Life isn't always fair;
- And maybe it was my fault.

Common Sense lived by simple, sound financial policies (don't spend more
than you can earn) and reliable strategies (adults, not children, are in
charge).

His health began to deteriorate rapidly when well-intentioned but
overbearing regulations were set in place. Reports of a 6-year-old boy
charged with sexual harassment for kissing a classmate; teens suspended from
school for using mouthwash after lunch; and a teacher fired for reprimanding
an unruly student, only worsened his condition.

Common Sense lost ground when parents attacked teachers for doing the job
that they themselves had failed to do in disciplining their unruly children.

It declined even further when schools were required to get parental consent
to administer sun lotion or an aspirin to a student; but could not inform
parents when a student became pregnant and wanted to have an abortion.

Common Sense lost the will to live as the churches became businesses; and
criminals received better treatment than their victims.

Common Sense took a beating when you couldn't defend yourself from a burglar
in your own home and the burglar could sue you for assault.

Common Sense finally gave up the will to live, after a woman failed to
realize that a steaming cup of coffee was hot. She spilled a little in her
lap, and was promptly awarded a huge settlement.

Common Sense was preceded in death,
-by his parents, Truth and Trust,
-by his wife, Discretion,
-by his daughter, Responsibility,
-and by his son, Reason.

He is survived by his 5 stepbrothers;
- I Know My Rights
- I Want It Now
- Someone Else Is To Blame
- I'm A Victim
- Pay me for Doing Nothing

Not many attended his funeral because so few realized he was gone.

If you still remember him, pass this on. If not, join the majority and do
nothing.













 
 







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Tuesday, April 21, 2015

The computer swallowed Grandma and Yavne Yeshiva and Kibbutz



Yavna the Yeshiva and the Kibbutz

https://youtu.be/m8eCzD8ac78


Have Courage to Change

Whenever we have repeated a pattern many times, it is difficult to change. But all patterns ultimately can in fact be changed. It is a question of having a clear goal - and then being motivated to take action.

It is easier to change patterns when two parties are willing to work together. If you are the only one, it takes more strength, more courage, and more resilience. That's why cooperation is essential in a marriage.

The Almighty leads a person on the path on which he wants to go. May He give you the wisdom to make the right decisions and choices, and the wisdom to know when to open your mouth.

Love Yehuda Lave

Battery powered rocket powerful enough to blast satellites into orbit

Rocket Lab, which is based in Los Angeles and has a launch site in New Zealand, will charge $5m per launch for its electric electron rocket.

Read the full story:

http://www.dailymail.co.uk/sciencetech/article-3040594/The-battery-powered-rocket-powerful-blast-satellites-orbit.html

16 April 2015





US Navy's drone CANNON can shoot 30 swarm bots in under a minute

The US Navy says its system will be able to launch a 30 drone 'swarm' in under a minute. The can work together to attack or defend sites, helping sailors and marines.

Read the full story:

http://www.dailymail.co.uk/sciencetech/article-3040891/Watch-Navy-s-drone-CANNON-Weapon-shoot-30-swarm-bots-minute-new-era-warfare.html

16 April 2015


https://youtu.be/lTBqtnpsQTQ

These pictures were taken in 2010.
The earth looks so peaceful from a distance .....

Shalom






Monday, April 20, 2015

Message from the Queen and Technion Scientists reach breakthrough on Cancer


Avoid Arguments With Silence

Be careful not to become involved in quarrels with your friends. Arguments will only create distance between you and others.

The most effective approach to avoid needless arguments is to master the ability to remain silent. You don't have to say everything you think of saying. At times there is an actual need to clarify a specific point and it's appropriate to speak up. But a large percentage of arguments come from making comments that don't need to be made.

Like I leaned from my teacher Rabbi Pliskin, this doesn't mean that there are no exceptions to this rule. When someone accuses of an injustice and you let it lie, there are times when you have to open your mouth.. Many times silence is considered an acceptance of the unjust charges and if the circumstances are safe, you are entitled to defend yourself with your mouth.

Many times you are accused of wrongdoing that you are innocent of (or at least you did the best you could under the circumstances). There is only justice in G-d's court. In the human court there are no guarantees of fair treatment.

Love Yehuda Lave












A MESSAGE FROM THE QUEEN

To the citizens of the United States of America from Her Sovereign Majesty Queen Elizabeth II

In light of your failure in recent years... to nominate competent candidates for President of the USA and thus to govern yourselves, we hereby give notice of the revocation of your independence, effective immediately. (You should look up 'revocation' in the Oxford English Dictionary.)

Her Sovereign Majesty Queen Elizabeth II will resume monarchical duties over all states, commonwealths, and territories (except North Dakota, which she does not fancy).

Your new Prime Minister, David Cameron, will appoint a Governor for America without the need for further elections.

Congress and the Senate will be disbanded. A questionnaire may be circulated next year to determine whether any of you noticed.

To aid in the transition to a British Crown dependency, the following rules are introduced with immediate effect:

-----------------------

1. The letter 'U' will be reinstated in words such as 'colour,' 'favour,' 'labour' and 'neighbour.' Likewise, you will learn to spell 'doughnut' without skipping half the letters, and the suffix '-ize' will be replaced by the suffix '-ise.' Generally, you will be expected to raise your vocabulary to acceptable levels. (look up 'vocabulary').

------------------------

2. Using the same twenty-seven words interspersed with filler noises such as ''like' and 'you know' is an unacceptable and inefficient form of communication. There is no such thing as U.S. English. We will let Microsoft know on your behalf. The Microsoft spell-checker will be adjusted to take into account the reinstated letter 'u'' and the elimination of '-ize.'

-------------------

3. July 4th will no longer be celebrated as a holiday.

-----------------

4. You will learn to resolve personal issues without using guns, lawyers, or therapists. The fact that you need so many lawyers and therapists shows that you're not quite ready to be independent. Guns should only be used for shooting grouse. If you can't sort things out without suing someone or speaking to a therapist, then you're not ready to shoot grouse.

----------------------

5. Therefore, you will no longer be allowed to own or carry anything more dangerous than a vegetable peeler. Although a permit will be required if you wish to carry a vegetable peeler in public.

----------------------

6. All intersections will be replaced with roundabouts, and you will start driving on the left side with immediate effect. At the same time, you will go metric with immediate effect and without the benefit of conversion tables. Both roundabouts and metrication will help you understand the British sense of humour.

--------------------

7. The former USA will adopt UK prices on petrol (which you have been calling gasoline) of roughly $10/US gallon. Get used to it.

-------------------

8. You will learn to make real chips. Those things you call French fries are not real chips, and those things you insist on calling potato chips are properly called crisps. Real chips are thick cut, fried in animal fat, and dressed not with catsup but with vinegar.

-------------------

9. The cold, tasteless stuff you insist on calling beer is not actually beer at all. Henceforth, only proper British Bitter will be referred to as beer, and European brews of known and accepted provenance will be referred to as Lager. South African beer is also acceptable, as they are pound for pound the greatest sporting nation on earth and it can only be due to the beer. They are also part of the British Commonwealth - see what it did for them. American brands will be referred to as Near-Frozen Gnat's Urine, so that all can be sold without risk of further confusion.

---------------------

10. Hollywood will be required occasionally to cast English actors as good guys. Hollywood will also be required to cast English actors to play English characters. Watching Andie Macdowell attempt English dialect in Four Weddings and a Funeral was an experience akin to having one's ears removed with a cheese grater.

---------------------

11. You will cease playing American football. There is only one kind of proper football; you call it soccer. Those of you brave enough will, in time, be allowed to play rugby (which has some similarities to American football, but does not involve stopping for a rest every twenty seconds or wearing full kevlar body armour like a bunch of nancies).

---------------------

12. Further, you will stop playing baseball. It is not reasonable to host an event called the World Series for a game which is not played outside of America. Since only 2.1% of you are aware there is a world beyond your borders, your error is understandable. You will learn cricket, and we will let you face the South Africans first to take the sting out of their deliveries.

--------------------

13.. You must tell us who killed JFK. It's been driving us mad.

-----------------

14. An internal revenue agent (i.e. tax collector) from Her Majesty's Government will be with you shortly to ensure the acquisition of all monies due (backdated to 1776).

---------------

15. Daily Tea Time begins promptly at 4 p.m. with proper cups, with saucers, and never mugs, with high quality biscuits (cookies) and cakes; plus strawberries (with cream) when in season.

God Save the Queen!

 







Technion Scientists Reach Breakthrough in Cancer Study

Israeli scientists have reached a new breakthrough in finding a way to beat back cancer at the Technion Israel Institute of Technology.
Published: April 13th, 2015

Cancerous tumors.

Cancerous tumors.
Photo Credit: Courtesy, Technion Israel Institute of Technology

Israeli scientists are closer than ever to finding a way to beat back cancer at the Technion Israel Institute of Technology. The findings of the new study were published last week in the journal CELL.

The researchers discovered two cancer-suppressing proteins, according to information released via PR Newswire. They carried out the study in the world-famous laboratory of Nobel Prize laureate Professor Aaron Ciechanover, president of the Israel Cancer Society.

The team was led by research associate Dr. Yelena Dravtsova-Ivantsiv and worked together with physicians from Rambam, Carmel and Hadassah Medical Centers, all of whom are studying tumors and their treatments.

KPC1 – a vital pathway in the life of the cell – is responsible for the degradation of defective proteins that could damage the cell if not removed. The system tags these defective proteins and send them to the proteasome cellular complex to be destroyed.

The system also removes functional and healthy proteins that are no longer needed, thus regulating the processes the proteins control.

By the time a protein reaches the proteasome system it is already broken down but there are exceptions.

This study examined "p105" – a long precursor of a key regulator in a cell called "NF-kB" which has been identified as a link between inflammation and cancer.

The first person to suggest such a link was Dr. Rudolph Virchow, a German pathologist, in 1863. His research has been repeatedly confirmed over the years, and since the discovery of NF-kB 30 years ago, there have been many articles linking the cell to malignant transformation in tumors in various parts of the body.

The current research is focused on deciphering the decision-making mechanism that determines which process will be applied to the NF-kB cell. There are two, both connected to the "ubiquitin system" which produces a protein that greatly restricts the development of cancerous tumors.

1. Either a "ubiquitin" system component called KPC1 becomes involved and attaches ubiquitin to p105, thus shortening the protein to become "p50" ; or 2. Ubiquitination is mediated without KPC1 and instead by another component in the system, and p105 is degraded and destroyed completely.

In other words, the presence of high levels of KPC1 and p50 would mean the malignant growth is suppressed and healthy tissue appears to be protected, according to the present findings in the study.

The current research was conducted on lab mice as well as samples of human tumors. A strong connection was found between the suppression of malignancy and the level of the two proteins.

Professor Aaron Ciechanover, president of the Israel Cancer Society, noted that many more years will be required "to establish the research and gain a solid understanding of the mechanisms behind the suppression of the tumors. The development of a drug based on this discovery is a possibility, although not a certainty, and the road to such a drug is long and far from simple."

Ciechanover won the Nobel Prize in chemistry in 2004, together with Professors Avram Hershko (also from Technion) and Irwin Rose of the Fox Chase Cancer Center, for the discovery of the ubiquitin system. The current line of research is a continuation of that work.

About the Author: Hana Levi Julian is a Middle East news analyst with a degree in Mass Communication and Journalism from Southern Connecticut State University. A past columnist with The Jewish Press and senior editor at Arutz 7, Ms. Julian has written for Babble.com, Chabad.org and other media outlets, in addition to her years working in broadcast journalism.






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